If you are on the hunt for a delightful, comforting meal that’s both easy to prepare and packed full of all your favorite pizza flavors, this Pizza Casserole Recipe is exactly what you need. It brings together the perfect golden crust, savory pizza sauce, melty mozzarella, and spicy pepperoni in one cozy dish that satisfies every craving. Whether you’re feeding a crowd or treating yourself after a long day, this recipe turns pizza night into a warm, shareable experience with minimal fuss but maximum flavor.
Ingredients You’ll Need
Every ingredient here plays a crucial role in building layers of flavor and texture without making the process complicated. Each one is simple, yet essential to create that familiar pizza taste in casserole form.
- Bisquick baking mix: This shortcut mix forms the easy, buttery crust that soaks up all the sauce and cheese beautifully.
- Water: A small amount is all you need to bring the dough together — keep it just right for a soft, tender base.
- Garlic powder: Adds that subtle punch of savory depth that enhances the dough without overpowering it.
- Italian seasoning: A blend of herbs that gives the crust a fragrant hint of classic pizza flavor.
- Pizza sauce: The rich, tangy heart of the casserole that ties all the toppings and crust together.
- Pepperoni slices: For that signature spicy, meaty bite everyone expects on a pizza.
- Mozzarella cheese: Melts to gooey perfection, adding creaminess and that irresistible cheesy stretch.
How to Make Pizza Casserole Recipe
Step 1: Preheat and Prep
Start by heating your oven to 375°F (190°C). This ensures it’s ready and hot by the time you finish assembling. Lightly grease a 9×13 inch baking dish with cooking spray so the casserole slides out easily and doesn’t stick during baking.
Step 2: Make the Crust Dough
Grab a medium bowl and combine the Bisquick baking mix with garlic powder and Italian seasoning to infuse the dough with subtle flavors. Add water a little at a time and stir until you get a soft dough that’s easy to drop into the pan. If it’s too sticky or wet, sprinkle in a little more Bisquick to balance it out. This step is all about achieving a tender yet sturdy base that holds up to the toppings.
Step 3: Assemble the Layers
Divide your dough in half and drop spoonfuls evenly across the bottom of the prepared dish. This uneven layering creates a wonderfully rustic texture once baked. Drizzle half of your pizza sauce over the dough blobs. Follow up with pepperoni slices and a generous sprinkle of shredded mozzarella. Repeat these same layers with the remaining dough, sauce, pepperoni, and cheese for a layered delight that’s as flavorful as it is comforting.
Step 4: Bake Until Golden and Bubbly
Pop the casserole into your preheated oven and bake for 20 to 25 minutes. You’ll know it’s done when the cheese melts into bubbling pools of golden goodness and the crust takes on a gorgeous golden-brown color. This step is fun because the kitchen fills with the irresistible aroma of baked pizza goodness, making waiting almost impossible!
Step 5: Serve Warm and Enjoy
Once out of the oven, allow the casserole to sit for a few minutes so it firms up slightly. Cut into squares and serve warm for the ultimate comfort food experience that’s perfect for any night of the week.
How to Serve Pizza Casserole Recipe
Garnishes
Bring your Pizza Casserole Recipe to the next level by adding fresh garnishes right before serving. Sprinkle some chopped fresh basil or parsley for a burst of color and fresh flavor. A light dusting of crushed red pepper flakes can add a playful kick for spice lovers. For an extra touch of indulgence, drizzle a bit of garlic-infused olive oil over the top.
Side Dishes
This casserole pairs beautifully with simple sides that balance its rich, cheesy nature. A crisp Caesar salad or mixed greens with a tangy vinaigrette offer refreshing contrast. Roasted vegetables or a light garlic bread make excellent companions, completing a meal without overshadowing the main event.
Creative Ways to Present
For a fun twist, serve your Pizza Casserole Recipe in individual ramekins or mini cast iron skillets—this makes for a cozy, personal serving size that feels special. Alternatively, layering it in a clear glass baking dish lets everyone admire the colorful layers before digging in, enhancing the visual appeal of this comforting dish.
Make Ahead and Storage
Storing Leftovers
If you have any leftovers (and you probably will), cover the casserole tightly and store it in the refrigerator for up to 3 days. The flavors meld even more overnight, making those next-day bites even tastier!
Freezing
This Pizza Casserole Recipe also freezes well. Once fully baked and cooled, wrap it tightly with plastic wrap and foil, then freeze for up to 2 months. It’s convenient for busy days when you want a ready-to-go meal bursting with comforting flavors.
Reheating
To reheat, simply thaw in the refrigerator overnight if frozen, then warm in a 350°F oven until heated through and the cheese is melty once again. Avoid the microwave if you can—you’ll keep the crust nice and crispy by using the oven.
FAQs
Can I use a different kind of cheese?
Absolutely! While mozzarella is traditional for that melty, stretchy effect, feel free to mix in provolone, cheddar, or even a sprinkle of parmesan for an extra savory kick.
Is Bisquick necessary, or can I make my own dough?
Bisquick makes this recipe quick and easy, but if you prefer homemade dough, go for it. Just keep in mind the texture and rise might vary slightly, but the overall deliciousness will remain.
Can I add vegetables?
Yes, adding veggies like sliced mushrooms, bell peppers, or olives can add more flavor and nutrition. Layer them in with the pepperoni and cheese to customize your casserole.
How spicy is this Pizza Casserole Recipe?
The spice level mainly comes from the pepperoni and optional red pepper flakes. It’s mild by default but easy to adjust according to your preference.
What’s the best way to reheat leftovers?
Reheating in the oven at 350°F until warmed through preserves the crispy crust and melty cheese better than a microwave, which can make the crust soggy.
Final Thoughts
This Pizza Casserole Recipe has become one of those comforting go-to dishes that feels like a warm hug in food form. It’s simple to make but delivers on every pizza craving, making it perfect for busy nights or casual gatherings. Give it a try—once you taste those gooey layers of sauce, cheese, and pepperoni nestled on a golden crust, you’ll understand why it’s such a beloved favorite!
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Pizza Casserole Recipe
- Prep Time: 10 minutes
- Cook Time: 25 minutes
- Total Time: 35 minutes
- Yield: 6 servings
- Category: Casserole
- Method: Baking
- Cuisine: American
Description
This easy and delicious Pizza Casserole combines the flavors of classic pizza in a comforting casserole form, featuring a soft Bisquick crust layered with pizza sauce, pepperoni, and melted mozzarella cheese. Perfect for a family dinner or casual gathering, it bakes quickly to a golden bubbly masterpiece.
Ingredients
Crust
- 3 â…“ cups Bisquick baking mix
- 1 cup water
- 1 teaspoon garlic powder
- 1 ½ teaspoons Italian seasoning
Layers
- 1 (14-15 ounce) jar pizza sauce
- 6 ounces sliced pepperoni
- 2 cups shredded mozzarella cheese
Instructions
- Preheat and Prep: Preheat your oven to 375°F (190°C). Lightly grease a 9×13 inch baking dish with cooking spray to prevent sticking.
- Make Crust: In a medium bowl, mix together the Bisquick baking mix, garlic powder, and Italian seasoning. Slowly add 1 cup of water and stir until a soft dough forms. If the dough is too sticky, add a little more Bisquick; if too dry, add a bit more water to reach the soft dough consistency.
- Assemble Layers: Divide the dough in half. Drop spoonfuls of half the dough onto the bottom of the prepared baking dish, spreading slightly to form an even base. Drizzle half of the pizza sauce over the dough layer. Next, evenly layer half of the pepperoni slices and then half of the shredded mozzarella cheese. Repeat with the remaining dough, pizza sauce, pepperoni, and cheese to create a second layer.
- Bake: Place the casserole in the preheated oven and bake for 20-25 minutes, or until the cheese is melted and bubbly and the crust is golden brown around the edges.
- Serve: Remove the casserole from the oven, allow it to cool slightly, then cut into squares. Serve warm and enjoy the comforting pizza flavors in a casserole form.
Notes
- You can customize the toppings to your liking by adding vegetables like bell peppers or mushrooms.
- Use a mixture of mozzarella and cheddar cheese for a different flavor profile.
- To make it spicier, add red pepper flakes to the sauce or dough mix.
- Ensure the dough is soft but not too sticky for easier spreading in the pan.
- Leftovers can be refrigerated and reheated in the oven for best texture retention.
